CERAMIDI – the foundation of healthy and radiant skin
The skin is our largest organ and plays a key role in protecting the body from harmful external influences and maintaining internal balance. To function effectively, it is important to be well hydrated and protected from moisture loss. Ceramides are one of the key factors that allow the skin to perform its role. These little-known compounds are the true foundation of healthy and radiant skin.
Composition of the skin (lipid) barrier
The skin is made up of three layers: the epidermis (epidermis), dermis (dermis) and hypodermis (hypodermis). The epidermis also has several layers, including the stratum corneum, where ceramides are found.

Ceramides are therefore are found in the upper layers of the skin and act as a foundation that maintains the integrity of the skin barrier. The skin barrier is the protective layer of the skin that acts as a barrier against moisture loss and the ingress of irritants. This layer is crucial for keeping the skin hydrated and preventing dryness, flaking and irritation. Without a proper barrier, the skin would lose its ability to retain moisture, with negative consequences for its health and appearance.
The skin barrier, also known as the lipid barrier or lipid barrier, is a complex structure in the upper layer of the skin that plays a key role in maintaining skin health and functionality. It is composed of various lipids, including ceramides, fatty acids, cholesterol and other components. Together, they form a strong barrier that reduces moisture loss from the skin and prevents the penetration of unwanted substances.
Distribution of components in the lipid barrier:
Ceramides: typically make up about 50% to 60% of the lipids in the lipid barrier. This means that ceramides are a major component and are key to maintaining skin integrity, hydration and protection.
Fatty acids: such as linoleic acid, linolenic acid, oleic acid and others, are also an important part of the lipid barrier. Their proportion is usually half that of ceramides.
Cholesterol: present in the lipid barrier in smaller amounts than ceramides and fatty acids, but still plays a key role in the formation of a stable barrier structure.
Other components: in addition to ceramides, fatty acids and cholesterol, there are other components such as free fatty alcohols, sphingosines and other lipid molecules. These are smaller in proportion but still contribute to the overall composition of the lipid barrier.

The role of ceramides is to provide strength, elasticity and hydration to the skin barrier. Ceramides help regulate water loss from the body and prevent irritants, microbes and other harmful substances from penetrating the skin. They also play a role in maintaining the pH level of the skin and prevent dryness and irritation.
Skin plays an important role not only in improving a person’s appearance, but also in protecting and improving health. The human body is made up of about 70% water. If the skin does not maintain an adequate moisture content in the body, it can be life-threatening. In addition, the skin prevents harmful elements from the external environment from entering the body. Therefore, the role of the skin barrier is extremely important.
If cement plays an important role in binding the bricks together to build a strong wall, then the skin is strengthened by keratinised cells (the dead skin layer) and lipid compounds that fill the spaces between the keratinised cells in the outermost layer of the skin.

Skin barrier damage, dry skin and ceramides
The skin type characteristic of a damaged skin barrier is dry skin. In dry skin, water quickly disappears, leaving the skin drier and more susceptible to invasion by harmful elements from the external environment, causing irritation or allergies. Among the hundreds of lipid compounds within dry skin, a deficiency of ceramides is particularly dangerous. Skin deficient in ceramides does not have a normally formed skin barrier, but rather a broken skin barrier (see figure below).

Ceramides and humectants
As you may have seen by now, both dry and sensitive skin lacks ceramides or has an abnormal lipid structure (we call it a broken lipid barrier). Ceramide deficiency causes various skin problems, but ceramides alone cannot effectively restore the lipid barrier, so it is important to combine ceramides with moisturisers.
Ceramides therefore work in tandem with other lipid molecules, such as cholesterol and fatty acids, and with the proteins that make up skin cells. Together, they form a solid structure that connects skin cells to each other. This structure acts like a wall, reducing moisture loss from the skin and preventing the ingress of unwanted substances. Ceramides are key building blocks that, together with moisturisers (such as glycerol, hyaluronic acid, betaine, panthenol, etc.), allow the skin to stay hydrated, protected and resistant to external agents.
The role of ceramides in skin ageing
Because of their role in maintaining the skin barrier, ceramides have a key influence on the skin ageing process. As we age, the skin’s natural production of ceramides decreases, which can lead to a weakened protective layer. As a result, the skin becomes drier, loses its elasticity and wrinkles and fine lines may appear. Adding ceramides to your skincare routine can go a long way in restoring the skin’s lipid balance, reducing the signs of ageing and maintaining a healthy and youthful appearance.
Benefits of using products with ceramides
Skincare products containing ceramides are becoming increasingly popular for their many benefits. Using these products can help to strengthen the skin barrier, reduce moisture loss, improve elasticity and reduce the appearance of wrinkles and fine lines. Ceramides are particularly valuable for people with dry skin, sensitive skin or skin showing signs of ageing. Products with a high concentration of ceramides, such as creams, lotions and serums, can help to restore the skin’s natural structure and can thus help to restore radiance, smoothness and a healthy appearance.

Incorporating ceramides into daily care
How can you incorporate ceramides into your daily skincare routine? The first step is to choose products that contain ceramides as one of their key ingredients. Whether you are looking for creams, serums or lotions, pay attention to the composition of the products. In addition, it is important to cleanse your skin regularly and properly and to use skincare products that are adapted to your skin type.
Here are some tips on what to look for in skincare products:
Class I, II and III ceramides: look for products that contain these types of ceramides (you’ll also find type III ceramides under the name ceramides np), as they are important building blocks for keeping skin hydrated and protecting against moisture loss. These ceramides help to keep skin soft, smooth and supple.
Cholesterol: works with ceramides and fatty acids to form the skin barrier. Products containing cholesterol can support the skin’s protective function.
Fatty acids: linoleic, linolenic and oleic acid, complement ceramides and cholesterol in the formation of the skin barrier. Look for products that contain a variety of fatty acids.
Niacinamide (vitamin B3): this ingredient is not directly a ceramide, but is known for its ability to enhance the skin’s natural production of ceramides. Products with niacinamide may help to improve the functionality of the skin barrier.
Hyaluronic acid: although not a ceramide, hyaluronic acid is a popular ingredient for hydrating the skin. It can help maintain skin moisture and increase skin elasticity.
As I mentioned earlier, although the lipid barrier plays a key role in keeping the skin hydrated and protected, the use of moisturisers is still necessary to maintain optimal hydration levels. Oil-based facial care products can be useful for certain skin types and in certain situations, but they may not be sufficient on their own, and you should definitely keep hydration in mind when using oil-based products.
Are ceramides suitable for all skin types?
Ceramides are key building blocks for all skin types. Whether you have dry, oily, normal or combination skin, ceramides are important for maintaining healthy and balanced skin. Each skin type has its own unique characteristics, but in all cases ceramides are important for maintaining hydration, protection and the integrity of the skin barrier. Even if you have oily skin that produces more sebum, the skin barrier can be weakened, which increases moisture loss. The same applies to dry skin, where the skin barrier is often weakened, leading to dryness and sensitivity.
Ceramides help to keep the skin barrier in optimal condition, regardless of skin type. They reduce moisture loss, protect against external influences, help repair damaged skin and maintain its elasticity and smoothness. When choosing skincare products, it is important to consider the needs of your skin.
Products containing ceramides can be beneficial for all skin types, but are particularly important for people with dry skin, sensitive skin or signs of ageing.

Which ingredients to look for in products related to skin type and establishment or. strengthen the skin barrier?
Dry skin:
Ceramides: look for products with different types of ceramides to support skin barrier integrity and hydration.
Glycerol: is an excellent humectant that attracts and retains moisture in the skin.
Hyaluronic acid: this ingredient will help retain moisture and improve hydration.
Fatty acids: oils rich in omega-3 and omega-6 fatty acids can support the lipid barrier.
Oily and acne-prone skin:
Light oil ingredients: look for oils such as jojoba or squalane that won’t be too heavy for oily skin.
Niacinamide: helps regulate sebum secretion and reduce inflammation.
Salicylic acid: can help clean pores and prevent acne.
Sensitive skin:
Ceramides and lipids: to support the skin barrier and reduce sensitivity.
Allantoin: soothes and reduces irritation.
Oat Extract: has soothing properties.
Bisabolol: a natural ingredient that soothes irritated skin.
Which NANU products contain ceramides or. help strengthen the skin barrier?
V rich nourishing cream and antioxidant cream contains high concentrations of ceramides in company with effective moisturisers and linoleic acid and other fatty acids.
Intensive Moisturising FluidThis moisturiser, which is designed for slightly more oily skin, contains light oils full of linoleic and linolenic acids and sterols, as well as an extremely active ingredient that also helps to maintain beautiful skin, niacinamide.
Conclusion
Ceramides are among the most praised and sought-after skincare ingredients in recent years. Why? Because they are exceptional. They are beneficial for all skin types and conditions.
As we age or have dry or damaged skin, we notice a loss of ceramides in the skin. By applying ceramides to the top layer of the skin, we help the skin to repair itself. In fact, it is the ceramides that improve the appearance of our skin and make it look more youthful and radiant. Because without a strong skin barrier, applying even the most effective and rich products is pointless. So make sure you’re strengthening the skin barrier first and foremost, then everything else your skin needs to look even more radiant and healthy.
Ceramides are an essential ingredient for the health and beauty of our skin. Their role in maintaining the skin barrier, hydration and protection against external agents is crucial for maintaining healthy-looking skin. By choosing products containing ceramides, you can take care of your skin and provide it with the necessary building blocks for radiance and vitality.
Sources:
https://www.webmd.com/beauty/what-to-know-about-ceramides-for-skin
https://pubmed.ncbi.nlm.nih.gov/12553851/
https://www.mdpi.com/2079-9284/6/3/52
http://zeroid.com/main/brand.asp?cate=272&Pcate=267&Mcate=269
https://innovist.com/blogs/news/ceramides-in-your-skincare-routine
https://www.sciencedirect.com/topics/neuroscience/ceramide
Hannun, Y.A. and Obeid, L.M., 2011. Many ceramides. Journal of Biological Chemistry, 286(32), pp.27855-27862.
Chaurasia, B. and Summers, S.A., 2015. Ceramides-lipotoxic inducers of metabolic disorders. Trends in Endocrinology & Metabolism, 26(10), pp.538-550.
Grösch, S., Schiffmann, S. and Geisslinger, G., 2012. Chain length-specific properties of ceramides. Progress in lipid research, 51(1), pp.50-62.
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